For Prostate Health

What is Beta-Sitosterol?

Beta-sitosterol is a type of phytosterol, which are molecules that form cell membranes in plant cells. Beta-sitosterol is the most abundant plant sterol in the human diet and is naturally occurring in certain vegetables, fruits, nuts, and seeds.

Beta-sitosterol (BS) is one of the several phytosterols with a chemical structure similar to that of cholesterol. Aside from having a similar structure to cholesterol, it can also help to manage cholesterol levels in the body. The micronutrient is said to have many beneficial effects and for centuries, people have looked to beta-sitosterol for its medicinal properties and anti-inflammatory purposes.

Green leaves containing the beta-sitosterol plant compound are shown as ingredients in prostate supplements.

Beta-sitosterol For Men

Both men and women can benefit from the medicinal properties of beta-sitosterol, however, it is often used in men to treat an enlarged prostate, a non-cancerous condition known as benign prostatic hyperplasia, or BPH. As researchers continue to learn more about the medicinal properties of beta-sitosterol, many studies have proven that prostate supplements with beta-sitosterol are more effective for treating BPH than those without it. The compound works to inhibit the activity of an enzyme called 5-alpha-reductase, which is a key trigger in the development of BPH and prostate cancer.

BPH is a common condition that occurs due to the natural aging process in men. As men grow older, the prostate gland may enlarge, resulting in irritative or obstructive symptoms affecting day-to-day activities. Although BPH itself is not fatal, many men report worsening symptoms over time, if left untreated. The use of prostate supplements with beta-sitosterol has been used to relieve or improve symptoms associated with BPH by increasing the urine flow rate.

Are There Any Side Effects?

One of the great things about taking beta-sitosterol for prostate health is that there are very few side effects that have been reported with the supplement. It is generally safe for most people and the most common mild side effects that have been reported in studies are nausea, indigestion, gas, diarrhea, or constipation.

Although there has been no evidence to suggest that prostate supplements with beta-sitosterol might cause an interaction with any medication, it is still recommended to talk to your doctor before starting any supplement.

Why We Included it in Prost-P10x

When we were formulating our men’s prostate health supplement, we made sure to include the best ingredients that were clinically proven to promote prostate health.

Prost-P10x is a prostate supplement packed with beta-sitosterol and other vitamins and minerals that support prostate health. Our supplement is formulated to promote healthy prostate size, normal urination flow, improved urological health, and inflammation support in men.

Clinical Trials For Beta-Sitosterol For Men

There have been many studies to evaluate the use of beta-sitosterol for prostate health support. Below is the abstract from a study called “ A double blind, placebo-controlled randomized comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency” by Sudeep, H.V., Thomas, J.V. & Shyamprasad, K.

“Subjects aged 40–65 years with symptomatic BPH were randomized to 12-week double-blind treatment with 500 mg doses of β-sitosterol enriched saw palmetto oil, conventional saw palmetto oil and placebo orally in the form of capsules (n = 33 in each group). BPH severity was determined using the International Prostate Symptom Score (IPSS), uroflowmetry, serum measurement of prostate specific antigen (PSA), testosterone and 5α-reductase. During the trial, the androgen deficiency was evaluated using Aging Male Symptoms (AMS) scale, the Androgen Deficiency in the Aging Male (ADAM) questionnaire, serum levels of free testosterone. Results: Subjects treated with β-sitosterol enriched saw palmetto oil showed significant decrease in IPSS, AMS and ADAM scores along with reduced postvoiding residual volume (p < 0.001), PSA (p < 0.01) and 5α-reductase from baseline to end of 12-week treatment as compared to placebo. There was also a significant increment in the maximum and average urine flow rate (p < 0.001), and serum free testosterone level of subjects treated with enriched saw palmetto oil as compared to placebo.
This study demonstrates the efficacy of β-sitosterol enriched saw palmetto oil superior to conventional oil thus extending the scope of effective BPH and androgen deficiency treatment with improved quality of life through the intake of functional ingredients.”

BMC Urol 20, 86 (2020)